Antibiotic Dosage Adjustments in CKD: Aminoglycosides, Vancomycin, and Renal Clearance
The short answer Chronic kidney disease (CKD) can change how long certain antibiotics remain in the body. When the kidneys clear a drug more slowly, the same dose may produce higher or more prolonged drug exposure. This is particularly important with aminoglycosides such as gentamicin and amikacin and with vancomycin, because excessive exposure can increase … Read more